GPC3 and neoplasm: As a tumor marker with higher sensitivity than AFP, GPC3 can be used not only for the diagnosis of surgically resected samples, but also for the diagnosis of biopsy samples: Li B et al. compared the positive rate of GPC3 in surgically resected samples and that in biopsy samples, and found that the difference between them was small (80.0% vs 74.9%) 77.