SERPINH1 and endocarditis: For E. faecalis, 49 different virulence genes were identified, including genes coding for adhesins, aggregation substances, hyaluronidases, biofilm-associated proteins, lipopolysaccharide biosynthesis proteins, bile salt hydrolase, caseinolytic protease, capsular polysaccharide biosynthesis, cytolysin production, collagen binding protein, endocarditis specific antigen, virulence regulator/signal transduction system, fibrinogen adhesins, fimbrial biogenesis, metal binding lipoprotein, and serine protease (Supplementary File 1 Table S5).