CD8A and neoplasm: By using other rat-neu+ tumor cell lines (H2N100, H2N113, and H2N67) derived from the same BALB/c-NeuT mice as the TUBO cell line, transplanted onto full syngenic BALB/c-NeuT recipient mice Stagg et al. confirmed the essential role of CD8+ T cells in anti-neu mAb therapy.