Results confirmed that PDIA3P1 knockdown or miR-124-3p overexpression inhibited the protein level of p65 and its phosphorylated form, while PDIA3P1 overexpression or miR-124-3p inhibition increased their expression in our glioma cell models (Fig. 5d–f, Supplementary Fig. 4b). Here, RELA is linked to central nervous system cancer.