Similar to data in Fig. 6 showing that β-catenin is required for Vpu-mediated depletion of peroxisomal proteins, the expression of Vpu (Fig. 7B and C) or HIV-1 infection (Fig. 7D and E) of TCF-4 knockdown cells did not result in the upregulation of miRNAs that downregulate peroxisome biogenesis factors. Here, TCF4 is linked to HIV-1 infection.