HLA-B and small cell lung carcinoma: It has been also suggested that HLA-B*08:01 could improve the immunosurveillance against SCLC, as only 21% of LEMS smokers carrying this allele developed SCLC compared to 69% of non-carriers (p < 0.005, OR = 0.16, 95% CI [0.04–0.62]) [37].