However, monospecific anti-DFS70/LEDGF antibodies are not completely absent in SARD, since a recent international multicenter study led by Marvin Fritzler found a 1.1% frequency of these monospecific antibodies in a large cohort of patients with systemic lupus erythematosus (SLE) (13 out of 1137 patients) [127]. This evidence concerns the gene PSIP1 and systemic lupus erythematosus.