In line with this finding, presynaptic proteins, synapsin I (SYS) and synaptophysin (SYN), and postsynaptic protein, post-synaptic density 95 (PSD95) expression levels, were significantly increased in HF-MAC group compared with HF-FD group (all p < 0.05, Fig. 6d, e). This evidence concerns the gene SYN1 and hydrops fetalis.