Oddly, the importance of cell-cell adhesion’s association with β-cat has often being overlooked, particularly as E-cadherin (E-cad) has several critical functions, including facilitating the normal homeostasis and morphogenesis of the intestine [11, 12], serving as a tumor suppressor gene [13] and preventing invasiveness in carcinomas cells [14]. The gene discussed is CDH1; the disease is neoplasm.