We selected variables that were significant in the univariate analysis, and, after adjustments, the presence of diabetes mellitus, age, gender, ethnicity, calcitriol use during the first year of follow-up, antiplatelet drugs use, statin use, RAS inhibitors use, HD vintage, and C-reactive protein were excluded; and BMI, the presence of atherosclerotic disease and hypertension, and the 25(OH)D level remained in the model. The gene discussed is CRP; the disease is diabetes mellitus.