Massive studies have confirmed that METTL3 could cooperate with YTHDF2 not only in regulating cell differentiation25 but also causing tumour suppressor gene mRNA decay to impact the development and progression of tumour.23 Notably, as expected, compared with IgG pull‐down control, the methylated SETD7 and KLF4 mRNAs were abundant by the YTHDF2‐specific antibody in the RIP assay (Figure 5J). This evidence concerns the gene YTHDF2 and neoplasm.