To determine the effect of anthelmintic treatment on the pro-inflammatory cytokine milieu in T2DM, we measured the plasma levels of IL1α, IL-1β, IL-1Ra, IL-6, IL-12, IL-18, IL-23, IL-27, G-CSF and GM-CSF in Ss+ individuals before (pre-T) and 6 months after anthelmintic treatment (post-T). This evidence concerns the gene IL18 and type 2 diabetes mellitus.