GAS5 could inhibit the progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation [21]; SNHG15 interacted with and stabilized transcription factor Slug and promoted colon cancer progression [22]; Higher SNHG20 expression was significantly associated with advanced tumor, lymph node and metastases (TNM) stage and tumor size, as well as poorer overall survival [23]. This evidence concerns the gene SNHG15 and colorectal cancer.