Results showed that compared with adjacent normal tissues, SNHG1, GAS5, SNHG3-8, SNHG11, SNHG12, SNHG15-17, SNHG20, SNHG22 and SNHG25 were significantly upregulated in ccRCC tissues, while SNHG9, SNHG10, DANCR and SNHG14 were remarkably downregulated in ccRCC tissues. The gene discussed is SNHG22; the disease is nonpapillary renal cell carcinoma.