Interleukin-8 is expressed by hepatocytes during dengue infection,16 with reports of cytokines correlating with elevated transaminase levels17 and the expression of TNFα following the apoptosis of hepatocytes in dengue infection.18 Others reported a correlation between severity and IL-6 and TNFα levels.19 However, only limited data are available for the relationship between the increased expressions of cytokines with hepatitis and bleeding. The gene discussed is TNF; the disease is hepatitis A virus infection.