As we were unable to obtain a sufficient number of ccRCC‐CD133+CSCs for immunoblotting isolated mitochondria, we isolated mitochondria from a ccRCC immortalized cell line (RCC‐26) treated with R2TNF or left UT and observed that R2TNF induced the expression of TNFR2 and pSTAT3Ser727 (Figure 4E). This evidence concerns the gene PROM1 and nonpapillary renal cell carcinoma.