Quantification of flowcytometry (top) and immunofluorescence data (bottom) of CD133+cells from normal kidney (NK‐CD133+cells) and clear cell renal carcinoma (ccRCC‐CD133+CSCs) positive for CellROX® Green (marker of ROS generation) following siRNA targeting TNFR2 or STAT3 or negative controls (UT and NTsiRNA) for 72h/37°C or for immunostaining data treatment with wtTNF, R1TNF or R2TNF alone for 30min/37°C or post‐treatment with wtTNF after siRNA transfection (±NAC, ROS scavenger) for 1h/37°C. The gene discussed is STAT3; the disease is clear cell renal carcinoma.