Flow cytometry and IF analysis confirmed that wtTNF and R2TNF (not R1TNF), induce pVEGFR2Y1059, AktThr308, mToRSer2448, and PI‐3Kp110β in ccRCC‐CD133+ CSCs compared to UT controls (Figure 3A‐D). The gene discussed is PROM1; the disease is nonpapillary renal cell carcinoma.