CD274 and neoplasm: Interestingly, turning to other models of cancer, it has been shown that PD‐1 expression correlates negatively with phagocytic potency against tumor cells, and blockade of the PD‐1/PD‐L1 in vivo increases phagocytosis by macrophages, reduces tumor growth and lengthens the survival of mice in mouse models of cancer in a macrophage‐dependent fashion.49 From the viewpoint of the present study, we would like to explore the density and polarity of tumor‐infiltrating macrophages relative to the treatment states.