Cross talk between oncogenic Kras and Wnt/β‐catenin signaling has been reported in colorectal cancers, with its activity mediated through GSK3β or LRP6.48, 49 KrasVal12 enhanced the level of β‐catenin by inhibiting GSK3β, although this effect was not mediated by phosphorylation of GSK3β at Ser 9.49 The expression of p21Ras proteins is upregulated in the differentiation of HL‐60 cells,14 but the involvement of Kras in myeloid differentiation is less clear. This evidence concerns the gene KRAS and colorectal cancer.