Moreover, miR200b/c significantly upregulates Col 1α and Col 4α in MCs and diabetic mice.72 Wang el al showed that miRNA‐377 contributes to inhibition of p21‐activated kinase and superoxide dismutase and enhances fibronectin (FN) accumulation in mouse models of DKD.73 miRNA‐1207‐5p, which is upregulated by TGF‐β1, can increase expression of TGF‐β1, PAI‐1, and FN in MCs.74 Here, SERPINE1 is linked to diabetic kidney disease.