IL6 and primary biliary cholangitis: Immunohistochemistry on PBC patients has previously demonstrated release of cytokines typically associated with Th17 cells, specifically IL‐6, IL‐23, and CCL20.1, 5, 12 We found that many of these cytokines were up‐regulated by the cholangiocytes following senescence induction, although IL‐6 was by far the most abundant.