NFE2L2 and infection: Activation of nuclear factor‐erythroid‐2 related factor 2 (Nrf2) may be deregulated during the aging process.18 It is also known that Nrf2 controls GSH production and regeneration,19 and that a modified expression of Nrf2 can alter influenza virus entry and subsequent replication.20 Having found very low quantity of GSH in the lungs of old mice (Figure 1A), we first investigated Nrf2 expression in lung homogenate of old and young mice, then how it was influenced by both infection and GSH‐C4 treatment in old mice.