The latter process is mediated by the Niemann‐Pick C1‐Like 1 (NPC1L1) protein, a cholesterol transporter that is expressed on the bile canalicular membrane in humans.6, 7 Thus, we hypothesized that hepatic NPC1L1 could exacerbate NAFLD, including steatosis. The gene discussed is NPC1L1; the disease is metabolic dysfunction-associated steatotic liver disease.