For example, in breast cancer, STING and its downstream signaling may suppress the tumor or the cancer metastasis.33, 34 In contrast, STING is also required for cell survival and regrowth in breast cancer.35, 36 However, the results of the present study do not clarify whether the HBV‐triggered NF‐κB signaling pathway causes liver diseases and tumor development. This evidence concerns the gene NFKB1 and liver disorder.