TRPC6 and type 1 diabetes mellitus: A more recent study examined the effects of a single global and constitutive Trpc6 knockout in the Akita mouse model of type I diabetes.34 These workers observed reductions in albuminuria in Akita mice with Trpc6 knockout at 12 and 16 weeks of age compared to Akita mice that expressed wild‐type TRPC6 channels.