Patients with the ELOVL1 mutation exhibited abnormalities related to vision, such as decreased visual acuity, astigmatism, photophobia, and thinning of the nerve fiber layer in the retina.17, 18Elovl1−/−Tg(IVL‐Elovl1) mice exhibited a tendency to avoid the central area during the first 45 minutes of the open‐field test and lower activity levels in the light–dark transition test, despite the lack of detectable retinal histologic abnormality (Figures 4, 5, 6). Here, ELOVL1 is linked to Astigmatism.