Investigation of the protein expression levels of prenyltransferase subunits revealed reduced expression of FNTA, PGGT1B, and RABGGTA in schizophrenia DLPFC.118 This suggests that all forms of prenylation—farnesylation, typical geranylgeranylation, and Rab-specific geranylgeranylation—may be impaired in schizophrenia. The gene discussed is PGGT1B; the disease is schizophrenia.