In addition, we report high NRF3 expression levels in the HCT116 (colorectal carcinoma), H1299 (non-small-cell lung cancer), LNCaP (prostate adenocarcinoma), A-172 (glioblastoma), and T98G (glioblastoma multiforme) cell lines but not in the U2OS (bone osteosarcoma) and HeLa (cervical adenocarcinoma) cell lines (Fig. 1B; Fig. S2A). This evidence concerns the gene NFE2L3 and bone osteosarcoma.