RAGE receptors are associated with the cell membrane of most body cells and can combine with various ligands, including AGE, amphoterin, β-amyloid, S100/calgranulin [108,109,110,111,112], which results in the activation of proinflammatory pathways that play an important role in the etiopathogenesis of schizophrenia. The gene discussed is S100B; the disease is schizophrenia.