Liao and Leung [76] reported that tryptanthrin is able to inhibit the growth of the N-myc amplified human neuroblastoma LA-N-1 cells (IC50 = 15.8 ± 1.41 μM) as well as two other human neuroblastoma cell lines SH-SY5Y and SK-N-DZ, which induced cell cycle arrest at the G0/G1 phase. The gene discussed is MYCN; the disease is neuroblastoma.