MKI67 and neoplasm: Immunohistochemical analyses: Ki67 (% of tumor cells, estimate in 10% intervals if image counting tools are not available (more reproducible than hotspot counting)); Tumor infiltrating lymphocytes (number of CD8 positive lymphocytes per HPF); Viral status (MCPyV is positive when >1% of tumor cells stain independently of intensity when using the immunohistochemical clone CM2B4).