As shown in Figure 5, the expression levels of zbTRIM25 and its downstream genes, RIG-I, MAVS, TRAF3, IRF3, and IFN 1 decreased to some different extent at 24 h post RGNNV infection in miR-202-5p mimics transfected ZBE3 cells (Figure 6A). This evidence concerns the gene RIGI and infection.