Moreover, members of the SOCS family are induced by infections with various viruses, including human immunodeficiency virus-1, hepatitis C virus, hepatitis B virus, herpes simplex virus type 1, respiratory syncytial virus, Ebola virus, and varicella zoster virus, and subsequently contribute to viral replication and pathogenesis [14,15,16,18,19,33,34,35,36]. The gene discussed is CISH; the disease is infection.