To date, only three studies have revealed a correlation between CYP2B6 c.516G>T polymorphism and AL (Berkoz & Yalin, 2009; Daraki et al., 2014; Yuan et al., 2011), and one study report that the CYP2B6 c.516G>T polymorphism was not associated with AML prognosis (Alazhary et al., 2015). This evidence concerns the gene CYP2B6 and acute myeloid leukemia.