VEGFA and malignant colon neoplasm: Many growth factors are involved in different stages of CNV.24 Among these growth factors, VEGF is the most important.25 A previous study by us has demonstrated the inhibition role of SARI on VEGF expression in colon cancer cells.15 To further determine the underlying mechanism of SARI attenuating the severity of CNV, the choroidal tissues were collected for VEGF staining.