DKK1 and renal fibrosis: Additionally, although Wnt inhibitors such as DKK1 have inhibitory effects on activation of β‐catenin,59 however, the broad‐spectrum inhibition of multiple Wnts activity would certainly induce both good and bad effects as some Wnts may have the blocking effects on renal fibrosis.60, 61 Hence, to develop the therapeutics from the promoters of GSK3β would provide new insights to block the reactivated β‐catenin signalling in tubular cell injury and renal fibrosis.