GSK3B and renal fibrosis: The activation of Wnt/β‐catenin signalling is highly associated with oxidative stress, inflammation and cellular senescence.15, 16, 17, 18 Upon the binding of Wnt ligands to the receptors frizzled (Fzd) and lipoprotein receptor–related protein (LRP) 5/6, GSK3β activity is repressed, and then, β‐catenin would be released and activated to trigger cell injury and renal fibrosis.