Moreover, in a prospective study including 2,835 cases and 3,122 matched controls from 10 cohorts, circulating anti-Müllerian hormone that is usually produced by ovaries also correlated with BC risk, particularly with ER+/PR+ tumors, with a 60% higher risk for women in the top quartile as compared to the bottom quartile of anti-Müllerian blood concentration (32). The gene discussed is ESR1; the disease is breast cancer.