However, it is unclear if the IPF phenotype observed in CD151-null mice is strain-specific as differences in renal function in tumor formation (Li et al., 2013) has been observed between FVB/N background [generated using 129SvEv ES cells (Takeda et al., 2007; Tsujino et al., 2012)] versus C57BL/6 mice [generated from 129/Ola and C57BL/6 ES cells (Wright et al., 2004)]. Here, CD151 is linked to idiopathic pulmonary fibrosis.