Src oncogene at 64B (Src64B) and Src42A are capable of inducing tumourigenesis in eye-antennal imaginal discs when overexpressed by cooperating with Ras85DV12 – JNK signalling in these tumours is necessary for their neoplastic overgrowth and invasion, and the Raf-MAPK and Phosphoinositide 3-kinase (PI3K) signalling pathways act downstream of Ras85DV12 to facilitate this cooperation (Poon et al., 2018). This evidence concerns the gene MAPK8 and neoplasm.