Egr is suspected, and haemocytes appear to be attracted to tumourous tissue just as they are attracted to pre-tumourigenic tissue (Figure 3), though not necessarily by the same mechanism – Ras85DV12/scrib–/– tumours, in their undead-like state, have been shown to co-opt the activity of caspases to generate reactive oxygen species (ROS), which can attract haemocytes, which then activate JNK signalling and caspases in the tumourigenic cells, forming a feedback loop (Pérez et al., 2017). This evidence concerns the gene MAPK8 and neoplasm.