Lipolytic factors or hormones, such as tumor necrotic factor α (TNFα) (Oliff et al., 1987), interleukin-6 (IL-6) (Strassmann et al., 1992), Zinc-α2-glycoprotein (ZAG) (Bing et al., 2004), catecholamines, and natriuretic peptides (Kalra and Tigas, 2002), explain lipolysis in cancer cachexia. This evidence concerns the gene IL6 and cancer.