MSLN and neoplasm: Notably, TAAs can be proteins involved in tumor cell survival and proliferation, such as HER2, EGFR, p53, telomerase, survivin, and Ras, in tumor metabolism, such as folate-related proteins and glucose receptors (e.g., GLUT1), or other proteins such as MUC-1 and mesothelin (Vigneron, 2015).