LAP3 and infection: In the present study, in addition to the VirB6-4 (MC1_00820) ortholog described above, M16 family peptidase (MC1_01650) homolog, EHF_0125, and DNA mismatch repair protein MutS (MC1_02260) homolog, EHF_0723 had insertions, suggesting functions of these genes are universally dispensable for mammalian cell infection by members of the order Rickettsiales.