In order to verify our results, we compared the expression levels of THBS1 in AML patients and healthy control samples using the GSE13164 database; THBS1 was significantly lowly expressed in the PBMC of AML patients (Figure 3C), suggesting that low serum THBS1 expression might be due to the reduced secretion of PBMC. This evidence concerns the gene THBS1 and acute myeloid leukemia.