Then, we performed the gene enrichment analysis using the Metascape database (http://metascape.org); we found that the biological processes were significantly enriched in the AML patients, such as cytokine-mediated signaling, positive regulation of locomotion, leukocyte migration, peptidyl-tyrosine phosphorylation, regulation of MAPK cascade, JAK-STAT cascade, tyrosine kinase signaling pathway, etc. (Figure 1B). This evidence concerns the gene SOAT1 and acute myeloid leukemia.