Based on the data from ONCOMINE, the transcriptional levels of CXCL6, CXCL9, CXCL10, CXCL11, and CXCL16 in RCC tissues were significantly elevated while the transcriptional levels of CXCL3, CXCL7, and CXCL13 were significantly reduced in RCC vs. normal renal tissue. This evidence concerns the gene CXCL3 and renal cell carcinoma.