These data suggest that ALDOA, ARNT, C3, CALM1, CAMK2A, CCL28, CCR1, CCR2, CCR3, CCR4, CCR5, CCR8, CCR9, CCRL2, CDC42, CSNK1A1, CX3CR1, CXCR6, DRD3, GNAI2, GNB1, GNB2, GNGT1, GRK6, GRM6, GRM7, HEBP1, HGS, 1L12B, 1L23A, NMUR2, PDGFRB, PIK3CA, PPKCD, PTGER3, PTPN11, PXN, RAC1, RALB, SPARC, SSTR4, STAT2, STAT3, TAS2R3, TAS2R31, TAS2R4, VWF, WNT5A, XCR1, and GRM2 were primarily associated with the modulation and function of differentially expressed CXC chemokines in RCC (Figure 7E). The gene discussed is SPARC; the disease is renal cell carcinoma.