We found that 12 genes were differentially expressed in RCC compared with normal tissue (upregulation of CXCL1, CXCL2, CXCL5, CXCL6, CXCL9, CXCL10, CXCL11, CXCL13, and CXCL16; downregulation of CXCL3, CXCL7, and CXCL12). This evidence concerns the gene CXCL6 and renal cell carcinoma.