Luckily, it was revealed that chlorpromazine can downregulate the protein expression of PELP1 in gastric cancer dose-dependently, although we did not clarify the exact mechanism for downregulation of PELP1 targeted by chlorpromazine and cannot identify downregulation of PELP1 is the only or major mechanism for chlorpromazine to inhibit gastric cancer. This evidence concerns the gene PELP1 and gastric cancer.