IFNG and cancer: Methylobacteriaceae producing phytohormones has an anticancer effect. Depletion of Methylobacteriaceae increases the cancer potential. On the other hand, Corynebacterium, Staphylococcus and Actinomyces genera as well as Propionibacteriaceae induce interferon-gamma (IFN-γ) secretion from T- and NK-cells, permit cancer cells to escape from T- and NK-cells recognition, and upregulate cell proliferation signals.