IL1R1 and Miyoshi myopathy: Exposure of Nf2+/−;Cdkn2a+/− mice to asbestos in the presence of an IL-1 receptor (IL-1R) antagonist known as anakinra resulted in a significant delay MM development compared to that of asbestos-exposed mice given a vehicle control, i.e., 33 vs. ~22.5 weeks, respectively (55).