Erb-b2 receptor tyrosine kinase 2 (ERBB2) overexpression is correlated with increased metastasis of human cancers, and the depletion of SRRM2, splicing factor, arginine/serine-rich 1 (SFRS1), SFRS9, and SFRS10 proteins reduced the migration rate of ovarian cancer cells overexpressing ERBB2 (28). The gene discussed is ERBB2; the disease is cancer.