Recent studies showed that EGFL7 is involved in the pathology of certain solid tumors, including breast cancer (7), epithelial ovarian cancer (8), hepatocellular carcinoma (9), colorectal cancer (10), acute myeloid leukemia (11), and malignant glioma (12, 13), However, evidence regarding the role of EGFL7 in OS is still sparse (14, 20). Here, EGFL7 is linked to hepatocellular carcinoma.