The results confirmed that knockdown of TUBA1C significantly inhibited the pancreatic cancer cell proliferation (AsPC-1 and BxPC-3) (P < 0.05, Figure 3F) and enhanced the cell apoptosis in AsPC-1 and BxPC-3 cell lines (P < 0.05, Figure 3G). The gene discussed is TUBA1C; the disease is familial pancreatic carcinoma.