GZMB and cancer: GRβ has been demonstrated to be involved in the migration of bladder cancer and brain cancer (Mcbeth et al., 2016; Ying et al., 2013), and some other studies have also reported that GRβ levels are elevated in inflammatory diseases and cancers, leading to increased progression (Zhu et al., 2007; Marino et al., 2016; Psarra et al., 2005).