The latest research conducted by Heng-Yu Chang et al. showed that in prostate cancer cells, glycyrrhizin may block the EMT process by modulating HMGB1 initiated novel signaling pathway through Cdc42, GSK-3β, Snail, and E-cadherin Kinases (Chang et al., 2019). The gene discussed is HMGB1; the disease is prostate carcinoma.